Tag Archives: biology

Curious Minds 9.3: Targeted Protein Degradation

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Last night’s Curious Minds talk was a cracker!


Professor Alessio Ciulli runs one of the biggest and highest profile research teams in Dundee. He is a world leader in the field of Targeted Protein Degradation – a way to encourage a cell’s natural garbage-disposal mechanisms to remove rogue proteins.

 

TPD is a breakthrough method that has enabled the development of multiple new drugs for treating some of the most intractable cancers and other diseases. More than 30 drugs are currently in the approval pipeline with many more promised – and many are based on the Ciulli group’s work in Dundee.

A video of the evening is available on our YouTube channel:

Curious Minds 9.2: Circadian Rhythms and Diabetes

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For the second talk in our Curious Minds lecture series, Dr Brendan Gabriel from the University of Aberdeen spoke about the effects of circadian rhythms on metabolic disorders especially diabetes, including how disruptions such as shift work affect health.

A video of the evening can be seen on our YouTube channel:

https://youtu.be/Hs-kFVEjiQ0

Curious Minds 9.1: Brain Development, Prof David Price

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In a great start to our Curious Minds season last night. Professor David Price, from Edinburgh University, delved into the mysteries of early brain development.

He showed us how the early nervous system in a tiny foetus is already divided into functional areas and how a particular gene, PAX6, encourages or inhibits the growth of connections between those areas. And lots of good questions later in our discussion.

A fascinating peek into an enormously complicated subject.

A video of the talk is available on our YouTube channel: PSNS1867

https://youtu.be/_poMNXiLlEI

Curious Minds 8.5: Inside the World of Killer Fungi

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For the fifth in this series of Curious Minds lectures, Dr Delma Childers (University of Aberdeen) spoke to us about “killer fungi”.

Fungal diseases are an under-appreciated global health threat that are responsible for more than a million deaths per year. Delma is keen to raise public awareness about fungal infections and the growing problem of antimicrobial resistance.

Content Warning:

A couple of the slides have moderate gore. These are preceded by slides with an asterisk in the top-right corner by way of advance warning.

The video can be seen on our youtube channel at